Ryszard Ostaszewski

D. S. Wavhal, D. Koszelewski, C. Gulko, P. Kowalczyk, A. Brodzka, K. Kramkowski, R. Ostaszewski, „Mystery of the Passerini Reaction for the Synthesis of the Antimicrobial Peptidomimetics against Nosocomial Pathogenic Bacteria”, Int. J. Mol. Sci.

A. Brodzka, D. Koszelewski, A. Trzeciak, L. Ruzik, M. Grela, R. Ostaszewski, „The Influence of Ligands on the Pd-Catalyzed Diarylation of Vinyl Esters”, Molecules

TP. Kowalczyk, D. Koszelewski, A. Brodzka, J. K. Kramkowski, R. Ostaszewski, „Evaluation of Antibacterial Activity against Nosocomial Pathogens of an Enzymatically Derived α-Aminophosphonates Possessing Coumarin Scaffold”, Int. J. Mol. Sci.

D. Piechota, P. Wardaszka, W. Barańska-Rybak, M. Jaśkiewicz, W. Kamysz, M. Deptuła, M. Pikuła, R. Ostaszewski, „Interdisciplinary approach to synthesis, stability and antimicrobial activity of silver nanoparticles”, Adv. Dermatol. Allergol.

D. Koszelewski, P. Kowalczyk, A. Brodzka, A. Hrunyk, K. Kramkowski, R. Ostaszewski, „Enzymatic Synthesis of a Novel Coumarin Aminophosphonates: Antibacterial Effects and Oxidative Stress Modulation on Selected E. coli Strains”, Int. J. Mol. Sci.

J. Samsonowicz-Górski, A. Hrunyk, A. Brodzka , R. Ostaszewski, D. Koszelewski, „Chemoenzymatic cascade reaction as a sustainable and scalable access to para-quinols”, Green Chem.

D. Koszelewski, P. Kowalczyk, J. Samsonowicz-Górski, A. Hrunyk, A. Brodzka, J. Łęcka, K. Kramkowski, R. Ostaszewski, „Synthesis and Antimicrobial Activity of the Pathogenic E. coli Strains of p-Quinols: Additive Effects of Copper-Catalyzed Addition of Aryl Boronic Acid to Benzoquinones”, Int. J. Mol. Sci.

A. Samborski, P. Jankowski, R. Ostaszewski, „The influence of UV light on the course of fluorescent enzyme assays”, Prep. Biochem. Biotechnol.

A. Brodzka, D. Koszelewski, R. Ostaszewski, „Simultaneous Enantiodivergent Synthesis of Diverse Lactones and Lactams via Sequential One-Pot Enzymatic Kinetic Resolution–Ring-Closing Metathesis Reactions”, Molecules

D. Koszelewski, P. Kowalczyk, P. Śmigielski, J. Samsonowicz-Górski, K. Kramkowski, A. Wypych, M. Szymczak, R. Ostaszewski, „Relationship between Structure and Antibacterial Activity of α-Aminophosphonate Derivatives Obtained via Lipase-Catalyzed Kabachnik−Fields Reaction”, Materials

M. Kublicki, D. Koszelewski, A. Brodzka, R. Ostaszewski, „Wheat germ lipase: isolation, purification and applications”, Critical Reviews in Biotechnology

J. Samsonowicz-Górski, D. Koszelewski, P. Kowalczyk, P. Śmigielski,
A. Hrunyk, K. Kramkowski, A. Wypych, M. Szymczak, R. Lizut,
R. Ostaszewski, „Promiscuous Lipase-Catalyzed Knoevenagel–Phospha–Michael Reaction for the Synthesis of Antimicrobial β-Phosphono Malonates”, Int. J. Mol. Sci.

J. Samsonowicz-Górski, A. Brodzka, R. Ostaszewski, D. Koszelewski, „Intensification of Double Kinetic Resolution of Chiral Amines and Alcohols via Chemoselective Formation of a Carbonate–Enzyme Intermediate”, Molecules

A. Brodzka, P. Kowalczyk, D. Trzepizur, D. Koszelewski, K. Kramkowski, M. Szymczak, A. Wypych, R. Lizut, R. Ostaszewski, „The Synthesis and Evaluation of Diethyl Benzylphosphonates as Potential Antimicrobial Agents”, Molecules

Parul , P. Kowalczyk, D. Koszelewski, M. Szymczak, K. Kramkowski, A. Wypych, R. Ostaszewski, „Influence of Open Chain and Cyclic Structure of Peptidomimetics on Antibacterial Activity in E. coli Strains”, Molecules

J. Samsonowicz-Gorski, A. Brodzka, R. Ostaszewski, D. Koszelewski, „Screening for amidoxime reductases in plant roots and Saccharomyces cerevisiae – development of biocatalytic method for chemoselective amidine synthesis”, Bioorganic Chemistry

A. Wołos, D. Koszelewski, R. Roszak, S. Szymkuć, M. Moskal, R. Ostaszewski, B. T. Herrera, J. M. Maier, G. Brezicki, J. Samuel, J. A. M. Lummiss, D. Tyler McQuade, L. Rogers, B. A. Grzybowski „Computer-designed repurposing of chemical wastes into drugs”, Nature

Gawdzik, P. Kowalczyk, D. Koszelewski, A. Brodzka, J. Masternak, K. Kramkowski, A. Wypych, R. Ostaszewski, „The Evaluation of DHPMs as Biotoxic Agents on Pathogen Bacterial Membranes”, Membranes

Kowalczyk, D. Koszelewski, B. Gawdzik, J.Samsonowicz –Górski, K. Kramkowski, A. Wypych, R. Lizut, R. Ostaszewski, „Promiscuous Lipase-Catalyzed Markovnikov Addition ofH-Phosphites to Vinyl Esters for the Synthesis of Cytotoxic α-Acyloxy Phosphonate Derivatives”, Materials

D. Koszelewski, D. Paprocki, A. Brodzka, A. Kęciek, M. Wilk, R. Ostaszewski, „The sustainable copper-catalyzed direct formation of highly functionalized p-quinols in water”, Sustainable Chemistry and Pharmacy

P. Kowalczyk, M. Szymczak, M. Maciejewska, Ł. Laskowski, M. Laskowska, R. Ostaszewski, G. Skiba, I. Franiak-Pietryga, „All That Glitters Is Not Silver—A New Look at Microbiological and Medical Applications of Silver Nanoparticles ”, Int. J. Mol. Sci.

E. Zaorska, M. Gawryś-Kopczyńska, R. Ostaszewski, M. Ufnal, D. Koszelewski, „Evaluation of thionolactones as a new type of hydrogen sulfide (H2S) donors for a blood pressure regulation”, Bioorg. Chem.

P. Kowalczyk, D. Trzepizur, M. Szymczak, G. Skiba, K. Kramkowski, R. Ostaszewski, „1,2-Diarylethanols—A New Class of Compounds That Are Toxic to E. coli K12, R2–R4 Strains”, Materials

R. Ostaszewski, M. Wilk, „Efficient assay for the detection of hydrogen peroxide via estimation of the enzyme promiscuous activity in the perhydrolysis reaction”, ChemBioChem

D. Koszelewski, A. Brodzka, A. Madej, D. Trzepizur, R. Ostaszewski, „Evaluation of gem-Diacetates as Alternative Reagents for Enzymatic Regio- and Stereoselective Acylation of Alcohols”, J. Org. Chem.

P. Kowalczyk, B. Gawdzik, D. Trzepizur, M. Szymczak, G. Skiba, S. Raj, K. Kramkowski, R. Lizut, R. Ostaszewski, „δ-Lactones—A New Class of Compounds That Are Toxic to E. coli K12 and R2–R4 Strains”, Materials

D. Trzepizur, A. Brodzka, D. Koszelewski, R. Ostaszewski, „Selective Esterification of Phosphonic Acids”, Molecules

M. Wilk, A. Brodzka, D. Koszelewski, J. Samsonowicz‐Górski, R. Ostaszewski, „Model Studies on the Enzyme-Regulated Stereodivergent Cascade Passerini Reaction”, Eur. J. Org. Chem.

M. Kublicki, D. Koszelewski, A. Brodzka, R. Ostaszewski, „Wheat germ lipase: isolation, purification and applications”, Crit. Rev. Biotechnol.

P. Kowalczyk, M. Wilk, P. Parul, M. Szymczak, K. Kramkowski, S. Raj, G. Skiba, D. Gołąbek-Sulejczak, P. Kleczkowska, R. Ostaszewski, „The Synthesis and Evaluation of Aminocoumarin Peptidomimetics as Cytotoxic Agents on Model Bacterial E. coli Strains”, Materials

D. Koszelewski, R. Ostaszewski, P. Śmigielski, A. Hrunyk, K. Kramkowski, Ł. Laskowski, M. Laskowska, R. Lizut, M. Szymczak, J. Michalski, K. Gawin, P. Kowalczyk, „Pyridine Derivatives—A New Class of Compounds That Are Toxic to E. coli K12, R2–R4 Strains”, Materials

J. Samsonowicz-Górski, P. Kowalczyk, M. Szymczak, K. Kramkowski, D. Koszelewski, A. Brodzka, R. Ostaszewski, „The Synthesis and Evaluation of Amidoximes as Cytotoxic Agents on Model Bacterial E. coli Strains”, Materials

D. Trzepizur, A. Brodzka, D. Koszelewski, M. Wilk, R. Ostaszewski, „Selective Palladium‐Catalyzed α,β‐Homodiarylation of Vinyl Esters in Aqueous Medium”, Eur. J. Org. Chem.

A. Brodzka, D. Koszelewski, R. Ostaszewski, „Dual Activity of Grubbs-Type Catalyst in the Transvinylation of Carboxylic Acids and Ring-Closing Metathesis Reactions”, J. Org. Chem.

P. Kowalczyk, A. Madej, M. Szymczak, R. Ostaszewski, „α-Amidoamids as New Replacements of Antibiotics—Research on the Chosen K12, R2–R4 E. coli Strains”, Materials

D. Paprocki, D. Koszelewski, A. Madej, A. Brodzka, P. Walde, R. Ostaszewski, „Evaluation of Biodegradable Glucose Based Surfactants as a Promoting Medium for the Synthesis of Peptidomimetics with the Coumarin Scaffold”, Chemistry Select

A. Madej, D. Koszelewski, D. Paprocki, A. Brodzka, R. Ostaszewski, „The amine as carbonyl precursor in the chemoenzymatic synthesis of Passerini adducts in aqueous medium”, Catal. Commun.

P. Kowalczyk, A. Madej, D. Paprocki, M. Szymczak, R. Ostaszewski, „Coumarin Derivatives as New Toxic Compounds to Selected K12, R1–R4 E. coli Strains”, Materials

E. Zaorska, L. Tomasova, D. Koszelewski, R. Ostaszewski, M. Ufnal, „Hydrogen Sulfide in Pharmacotherapy, Beyond the Hydrogen Sulfide-Donors”, Biomolecules

D. Paprocki, S. Berłożecki, R. Ostaszewski, „Environmental-friendly one-pot cascade synthesis of 3-cyanopiperidin-2,6-diones”, Environ. Chem. Lett.

A. Kęciek, D. Paprocki, D. Koszelewski, R. Ostaszewski, „Evaluation of alcohols as a substrates for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones under environmentally friendly conditions”, Catal. Commun.

D. Paprocki, M Wilk, A Madej, P Walde, R Ostaszewski, „Catalyst-free synthesis of α-acyloxycarboxamides in aqueous media”, Environ. Chem. Lett.

D. Koszelewski, F. Borys, A. Brodzka, R. Ostaszewski, „Synthesis of enantiomerically pure 5,6-dihydropyran-2-ones via chemoenzymatic one-pot DKR-RCM reaction”, Eur. J. Org. Chem.

M. Wilk, A. Brodzka, D. Koszelewski, A. Madej, D. Paprocki, A. Żądło-Dobrowolska, R. Ostaszewski, „The influence of the isocyanoesters structure on the course of enzymatic Ugi reactions”, Bioorg. Chem.

M. Wilk, D. Trzepizur, D. Koszelewski, A. Brodzka, R. Ostaszewski, „Synthesis of (E)-α,β-unsaturated carboxylic esters derivatives from cyanoacetic acid via promiscuous enzyme-promoted cascade esterification/ Knoevenagel reaction”, Bioorg. Chem.

D. Koszelewski, R. Ostaszewski, „The studies on chemoselective promiscuous activity of hydrolases on acylals transformations”, Bioorg. Chem.

P. Jankowski, A. Samborski, R. Ostaszewski, P. Garstecki, „Evaluation of droplet-based microfluidic platforms as a convenient tool for lipases and esterases assays”, Preparative Biochem. Biotech.

D. Koszelewski, R. Ostaszewski, „Biocatalytic promiscuity of lipases in carbon–phosphorus bond formation”, ChemCatChem

E. Zaorska, T. Hutsch, M. Gawryś-Kopczyńska, R. Ostaszewski, M. Ufnal, D. Koszelewski, „Evaluation of thioamides, thiolactams and thioureas as hydrogen sulfide (H2S) donors lowering blood pressure”, Bioorg. Chem.

D. Koszelewski, R. Ostaszewski, „Enzyme promiscuity as a remedy for the common problems with Knoevenagel condensation”, Chem. Eur. J.

A. Brodzka, D. Koszelewski, M. Zysk, R. Ostaszewski, „The mechanistic promiscuity of the enzymatic esterification of chiral carboxylic acids”, Catal. Commun.

D. Koszelewski, D. Trzepizur, E. Zaorska, A. Madej, A. Brodzka, D. Paprocki, F. Borys, M. Wilk, R. Ostaszewski, „Facile conversion of α-acyloxy amides into 3-hydroxy-lactams”, Eur. J. Org. Chem.

F. Borys, D. Paprocki, D. Koszelewski, R. Ostaszewski, „The studies on the chemoenzymatic synthesis of 2-benzyl-3-butenoic acid”, Catal. Commun.

A. Brodzka, F. Borys, D. Koszelewski, R. Ostaszewski, „Studies on the Synthesis of Endocyclic Enol Lactones via a RCM of Selected Vinyl Esters”, J. Org. Chem.

A. Madej, D. Koszelewski, D. Paprocki, A. Brodzka, R. Ostaszewski, „The sustainable synthesis of peptidomimetics via chemoenzymatic tandem oxidation-Ugi reaction”, RSC Adv.

S. Serrano-Luginbühl, S. Ruiz-Mirazo, R. Ostaszewski, F. Gallou, P. Walde, „Soft and dispersed interface- rich aqueous systems that promote and guide chemical reactions”, Nat. Rev. Chem.

E. Zaorska, M. Konop, R. Ostaszewski, D. Koszelewski, M. Ufnal, „Salivary Hydrogen Sulfide Measured with a New Self-immolative Coumarin-based Fluorescent Probe”, Molecules

D. Paprocki, A. Madej, D. Koszelewski, A. Brodzka, R. Ostaszewski, „Multicomponent reactions accelerated by aqueous micelles”, Front. Chem.

M. Cieplak, R. Ostaszewski, „Polymer membrane ion-selective electrodes as a convenient tool for lipases and esterases assays”, Preparative Biochem. Biotech.

A. Żądło-Dobrowolska, D. Koszelewski, D. Paprocki, A. Madej, M. Wilk, R. Ostaszewski, „Enzyme-promoted Asymmetric Tandem Passerni Reaction”, ChemCatChem

D. Koszelewski, D. Paprocki, A. Brodzka, R. Ostaszewski, „Enzyme mediated kinetic resolution of δ-hydroxy-α,β-unsaturated esters as a route to optically active δ-lactones”, Tetrahedron Asymm.

W. Kurek, D. Koszelewski, R. Ostaszewski, A. Żądło-Dobrowolska, „Bioreactor for the Continuous Purification of Simvastatin by Lovastatin Esterase”, Process Biochemistry

A. Żądło-Dobrowolska, J. H. Schrittwieser, B. Grischek, D. Koszelewski, W. Kroutil, R. Ostaszewski, „A Convenient Stereoselective Synthesis of 5-Hydroxy-3-oxoesters and 3-Hydroxy-5-oxoesters”, Tetrahedron Asymm.

A. Madej, D. Paprocki, D. Koszelewski, A. Żądło-Dobrowolska, A. Brzozowska, P. Walde, R. Ostaszewski, „Efficient Ugi reactions in an aqueous vesicle system”, RSC Adv.

D. Koszelewski, D. Paprocki, A. Madej, F. Borys, A. Brodzka, R. Ostaszewski, „Enzymatic tandem approach to Knoevenagel condensation of acetaldehyde with acidic methylene compounds in organic media”, Eur. J. Org. Chem.

A. Fryszkowska, D. Koszelewski, R. Ostaszewski, „Studies on asymmetric synthesis of bicyclomycin precursors. A chemoenzymatic route to chiral 2,5-diketopiperazines and 2-oxa-bicyclo[4.2.2]decane-8,10-diones”, Tetrahedron Asymm.

A. Drapala, D. Koszelewski, L. Tomasova, R. Ostaszewski, M. Grman, K. Ondrias, M. Ufnal, „Parenteral Na2S, a fast-releasing H2S donor, but not GYY4137, a slow-releasing H2S donor, lowers blood pressure in rats”, Acta Biochimica Polonica

A. Trzeciecka, S. Klossowski, M. Bajor, R. Zagozdzon, P. Gaj, A. Muchowicz, A. Malinowska, A. Czerwoniec, J. Barankiewicz, A. Domagala, J. Chlebowska, M. Prochorec-Sobieszek, M. Winiarska, R. Ostaszewski, I. Gwizdalska, J. Golab, D. Nowis, M. Firczuk, „Dimeric peroxiredoxins are druggable targets in human Burkitt lymphoma”, Oncotarget

A. Żądło, D. Koszelewski, F. Borys, R. Ostaszewski, „Evaluation of Pseudoenantiomeric Mixed Cabonates As Efficient Flurogenic Probes For Enantioselectivity Screening”, ChemBioChem

A. Żądło, J. H. Schrittwieser, D. Koszelewski, W. Kroutil, R. Ostaszewski, „Enantioselective Reduction of Ethyl 3-oxo-5-phenylpentanoate with Whole-Cell Biocatalysts”, Eur. J. Org. Chem.

D. Koszelewski, A. Brodzka, A. Żądło, D. Paprocki, D. Trzepizur , M. Zysk, R. Ostaszewski, „Dynamic Kinetic Resolution of 3-aryl-4-Pentenoic Acids”, ACS Catal.

D. Paprocki, D. Koszelewski, A. Żądło, P. Walde, R. Ostaszewski, „Environmentally Friendly Approach to α-Acyloxy carboxamides via a Chemoenzymatic Cascade”, RSC Adv.

A. Żądło-Dobrowolska, S. Kłossowski, D. Koszelewski, D. Paprocki, R. Ostaszewski, „Enzymatic Ugi Reaction with Amines and Cyclic Imines”, Chem. Eur. J.

A. Żądło-Dobrowolska, M. Szczygieł, D. Koszelewski, D. Paprocki, R. Ostaszewski, „Self-immolative Versatile Fluorogenic Probes for Screening of Hydrolytic Enzymes Activity”, Org. Biomol. Chem.

L. Tomasova, L. Dobrowolski, H. Jurkowska, M. Wróbel, T. Huc, K. Ondrias, R. Ostaszewski, M Ufnal, „Intracolonic Hydrogen Sulfide Lowers Blood Pressure in Rats”, Nitric Oxide

R. Ostaszewski, H. J. Hansen, „Oxidative 1,1’-coupling of Highly Alkylated Azulene-2-carboxylates”, Heterocycles

A. Żądło, D. Koszelewski, F. Borys, R. Ostaszewski, „Mixed Carbonates as Useful Substrates for a Fluorogenic Assay for Lipases and Esterases”, ChemBioChem

A. Muchowicz, M. Firczuk, M. Wachowska, M. Kujawa, E. Jankowska-Steifer, M. Gabrysiak , Z. Pilch, S. Kłossowski, R. Ostaszewski, J. Golab, „SK053 triggers tumor cells apoptosis by oxidative stress-mediated endoplasmic reticulum stress”, Biochemical Pharmacology

C. Wiśniewska, D. Koszelewski, M. Zysk, R. Ostaszewski, „The influence of cosolvent concentration on enzymatic kinetic resolution of trans-2-phenyl-cyclopropane-1-carboxylic acid derivatives”, Biocat. Biotrans.

M. Ufnal, A. Żądło, R. Ostaszewski, „TMAO, a small molecule of great expectations”, Nutrition

C. Wiśniewska, D. Koszelewski, M. Zysk, S. Kłossowski, A. Żądło, A. Brodzka, R. Ostaszewski, „Enzymatic synergism in the synthesis of β-keto esters”, Eur. J. Org. Chem.

D. Koszelewski, M. Zysk, A. Brodzka, A. Żądło, D. Paprocki, R. Ostaszewski, „Evaluation of a new protocol for enzymatic dynamic kinetic resolution of 3-hydroxy-3-(aryl)propanoic acids”, Org. Biomol. Chem.

D. Paprocki, D. Koszlewski, P. Walde , R. Ostaszewski, „Efficient Passerini reactions in an aqueous vesicle system”, RSC Adv.

Ryszard Ostaszewski

Publikacje

tematyka badań