Dr. Anna Domżalska-Pieczykolan and prof. Bartłomiej Furman publication in Angewandte Chemie International Edition

Publication entitled „Selective Approaches to α- and β-Arylated Vinyl Ethers” is a result of collaboration with prof. Carsten Bolm (RWTH Aachen) and was financed by the Iwanowska scholarship. Authors developed simple and efficient protocols for palladium-catalyzed regioselective α- and β-arylations of structurally diverse vinyl ethers. Both catalytic methods proceed under relatively mild reactions conditions applying to a broad substrate range including more complex compounds providing arylated glucal or isochromene. Lacking the common requirement of a large reagent excess, the transformations are highly economic and limiting the waste production. Moreover, results from computational studies (DFT) provided insight into the key factors determining the pronounced regio­selectivities of the investigated reactions.

Artykuł: https://onlinelibrary.wiley.com/doi/10.1002/anie.202109801

We congratulate the authors and wish them continued success in the future.