Head of the group
Assoc. Prof. Wojciech Chaładaj

Assistants
Dr inż. Maciej Dajek
Mgr Bartosz Bisek

PhD Students
M.Sc. Prachi Shah
M.Sc. Shrenik Sheth

NCN OPUS 2019/35/B/ST4/00599
Control of regio- and stereoselectivity of hydro- and carbofluoromethylation of alkynes via a sequence of hydro- or carbometallation and C-M functionalization”

Publications

M. Bao, K. Łuczak, W. Chaładaj, M. Baird, D. Gryko, M. P. Doyle, „Photo-cycloaddition reactions of vinyldiazo compounds”, Nat. Commun.

G. Sanil, M. Krzeszewski, W. Chaładaj, W. Danikiewicz, I. Knysh, Ł. Dobrzycki, O. Staszewska-Krajewska, M. Cyrański, D. Jacquemin, D. T. Gryko, „Unprecedented 1,2-Aryl Shift Accompanying Double Alkyne Benzannulation”, Angew. Chem. Int. Ed.

A. Błocka,   J. Ostapko, W. Chaładaj, „Tandem Pd-catalyzed annulation/coupling of acetylenic enamines with aryl triflates”, Chem. Commun.

F. Lucio-Martínez, W. Chaładaj, „Fluoroalkyl Iodides in Fluoroalkylative Difunctionalization of C−C Multiple Bonds”, Adv. Synth. Catal.

K. Orłowska, J. V. Santiago, P. Krajewski, K. Kisiel, I. Deperasińska, K. Zawada, W. Chaładaj, D. Gryko, „UV Light Is No Longer Required for the Photoactivation of 1,3,4-Oxadiazolines”, ACS Catal.

W. Chaładaj, A. Kołodziejczyk, S. Domański, „Gold(I)-Catalyzed Conia-ene Cyclization of Internal ϵ-Acetylenic β-Ketoesters under High Pressure.”, ChemCatChem

S. Domański, O. Staszewska-Krajewska, W. Chaładaj, Pd-Catalyzed Carbonylative Carboperfluoroalkylation of Alkynes. „Through-Space 13C–19F Coupling as a Probe for Configuration Assignment of Fluoroalkyl-Substituted Olefins.”, J. Org. Chem.

M. Białkowska, W. Chaładaj, I. Deperasińska, A. Drzewiecka-Antonik, A. E. Koziol, A. Makarewicz, B. Kozankiewicz, „Single molecules of terrylene in di-substituted naphthalenes crystallizing in the herringbone pattern.”, RSC Adv.

Research topics

  • Discovery of new Pd-catalyzed multicomponent transformations of alkynes enabling efficient direct assembly of simple building blocks into an elaborate target molecule.
  • Development of methods for fluoroalkylation of organic compounds, especially through tandem or sequential catalysis
  • Development of tandem reactions involving additions to alkynes and subsequent functionalization via cross-coupling
  • Investigation of the mechanisms of transition metal-catalyzed reactions