Head of the group
Dr hab. Michał Michalak

NCN SONATA BIS 2017/26/E/ST5/00510
“New N-heterocyclic carbene gold complexes: from catalytic activity to medical application”

Publications

M. Michalak, P. Czerwiński, K. Śniady-Maciążek, S. Musioł, O. Danylyuk, M. Wierzbicki, M. Tomasini, A. Poater, „Chiral NHC Ligands for Enantioselective Gold(I) Catalysis Under Aerobic Conditions: the Importance of Conformational Flexibility and Steric Hindrance of NHC Ligand on Reactivity”, Chem. Eur. J.

M. Chmielewski, R. Kutaszewicz, A. Ulikowski, M. Michalak, K. Wołosewicz, S. Stecko, B. Furman, „The Kinugasa Reaction”, Organic Reactions

A. Gornowicz, W. Szymanowski, K. Bielawski, Z. Kałuża, O. Michalak, A. Bielawska, „Mucin 1 as a Molecular Target of a Novel Diisoquinoline Derivative Combined with Anti-MUC1 Antibody in AGS Gastric Cancer Cells”, Molecules

M. Michalak, B. Bisek, M. Nowacki, M. Górecki, “Base-Catalyzed, Solvent-Free Synthesis of Rigid V-Shaped Epoxydibenzo[b,f][1,5]diazocines”, J. Org. Chem

P. Baczewska,K. Śniady, W. Kośnik, M. Michalak, “Acenaphthene-Based N-Heterocyclic Carbene Metal Complexes: Synthesis and Application in Catalysis”, Catalysts

I. Misztalewska-Turkowicz, K. H. Markiewicz, M. Michalak, A. Z. Wilczewska,  „NHC-copper complexes immobilized on magnetic nanoparticles: Synthesis and catalytic activity in the CuAAC reactions”, J. Catal.

K. Wolosewicz, M. Michalak, J. Adamek, B. Furman, „Studies on the Enantioselective Kinugasa Reaction: Efficient Synthesis of β-Lactams Catalyzed by N-PINAP/CuX Complexes”, Eur. J. Org. Chem.

P. Horeglad, M. Cybularczyk, A. Litwińska, A. M. Dąbrowska, M. Dranka, G. Z. Żukowska, M. Urbańczyk, M. Michalak, „Controlling the stereoselectivity of rac-LA polymerization by chiral recognition induced the formation of homochiral dimeric metal alkoxides”, Polymer Chemistry

P. Czerwiński, E. Molga, L. Cavallo, A. Poater, M. Michalak, „NHC–Copper(I) Halide-Catalyzed Direct Alkynylation of Trifluoromethyl Ketones on Water”, Chem. Eur. J.

Documents

Research topics

  • Synthesis of fluorinated azaheterocycles and propargylic alcohols via direct catalytic alkynylation on water catalyzed by N-heterocyclic carbene copper(I) complexes;
  • Immobilization of N-heterocyclic carbene copper(I) and copper(II) complexes on magnetic nanoparticles and its applications for the synthesis of heterocyclic compounds;
  • New chiral C1-symmetric N-heterocyclic carbene gold(I) and gold(III) complexes and its applications in enantioselective catalysis;
  • New fluorinated analogs of Tröger base ¬–dibenzo[b,f]diazocines.